The FRAME Lab in partnership with the University of Nottingham is a vital part of our work. Their dedication to developing, validating and sharing non-animal approaches is inspiring.
This past year at the lab we’ve seen:
- Five students complete their PhDs – congratulations to Drs Tarsitano, Edey, Heath, Alsolami and Rahman!
- Three areas of FRAME research published in four different journals:
- Non-Alcoholic Fatty Liver Disease: Zoe compares fat accumulation in liver cells from patients with human liver cell lines
- Breast Cancer: Wichitra explores how immune system interacts with breast cancer cell receptors to influence disease outcome
- Liver Fibrosis: Syedia’s papers on integrins as a drug target and therapetic potential of integrins in liver fibrosis
- Students representing the FRAME Lab at four conferences:
- International Conference on Molecular Neurobiology in Paris
- Midlands 3Rs Conference in Birmingham
- Pharmacology 2022 in Liverpool
- University of Nottingham Postgraduate Symposium
- FRAME funded work continuing in:
- Brain: human models of neuroinflammation in Parkinson’s disease and other conditions
- Liver: development of human liver models for toxicity, drug discovery and disease modelling
- Animal-free physiologically relevant cell culture: developing human cell culture systems that do not require supplementation with animal-derived materials