ATLA (Alternatives to Laboratory Animals) is published six times a year by FRAME, in partnership with SAGE Publishing, and has been a key scientific journal in the field of laboratory animal alternatives for more than 30 years.

ATLA is a peer-reviewed journal, intended to cover all aspects of the development, validation, implementation and use of alternatives to laboratory animals in biomedical research and toxicity testing. In addition to the replacement of animals, it also covers work that aims to reduce the number of animals used and refine the in vivo experiments that are still used.

The journal publishes original research papers, review articles, letters, comments and book reviews. It is of relevance to research scientists, academics, and those involved in regulatory affairs or in the field of animal ethics. The papers published commonly feature in vitro, ex vivo or in silico methods; surveys on the use of animals for education, research or testing purposes; humane teaching or medical training methods; and the optimisation and validation of novel or existing methods for use as non-animal alternatives.

Opinions expressed in any part of ATLA do not necessarily reflect the views of the FRAME Trustees or Staff, the Editors or Members of the Editorial Board. We are a member of Committee on Publication Ethics (COPE).

For more information on ATLA, including how to submit your article for consideration, please go to our SAGE Publishing platform

We are currently accepting submissions for a number of Special Collections. Find out more here. 

Visit the ATLA website Sign up for ATLA alerts

We are currently collating papers for a Virtual Special Collection spotlight on the following subjects:

• In silico tools
• Biobanking
• Educational resources
• Serum-free approaches

More information can be found in the documents below (click to enlarge).

Submission guidelines Submit your article