NAMs are new approach methodologies, sometimes called non-animal methods. NAMs refers to research specifically intended as a replacement for animal research. 

In our experience, there isn’t a simple answer. It’s about collaboration and remaining committed to our goal. 

We focus on three core areas: funding research, creating change, and sharing information. 

• Grants and funding to support researchers at every career stage to develop and grow confidence in non-animal research.
• Policy work to encourage policymakers to stay up to date on alternatives to animal testing. We also push for an overarching commitment across the government to replace animal research.
• Educational opportunities for researchers, students, policymakers, and our wonderful supporters on the importance of rigorous, ethical science and non-animal methods available. In our experience, there isn’t a simple answer. It’s about continuous, clear communication. 

The 3Rs are used worldwide by universities and legislators so it’s a helpful phrase to know. 

The 3Rs stand for: 

• Replacement 
• Reduction 
• Refinement 

The 3Rs’ primary aim is to replace animals with non-animal methods. There’s also a commitment to improve animal welfare where animal use is deemed unavoidable by regulatory bodies or researchers. 

FRAME’s focus is always the replacement of animals in laboratories. This is the first, and most challenging, of the 3Rs to implement. It involves researchers thinking differently about how to answer questions. One 3Rs criticism has been that too much time and money goes to the ‘easier’ goals of reduction and refinement. 

Find out more about the 3Rs in animal research.