FRAME is an independent charity, funded by corporate and individual donations and legacies. For more than 40 years we have played an active part in the campaign to promote alternatives to animal testing.

FRAME is dedicated to the development of new and valid methods that will replace the need for laboratory animals in medical and scientific research, education, and testing. Where the use of animals is currently necessary, FRAME supports the reduction of numbers involved to an unavoidable minimum and refinement of experimental procedures to minimise any suffering caused.

The charity was founded in London in 1969 by Dorothy Hegarty. The main aim of FRAME has always been to promote the Three Rs (Replacement, Reduction & Refinement) as a way forward for animal experimentation.

FRAME promotes the elimination of the need to use laboratory animals through various activities including campaigning, publication of a scientific journal (ATLA), office-based and laboratory research and through its educational work.

Through our own laboratory and desk-based research FRAME is continually investigating and developing new methods at the forefront of science. It also collaborates with other organisations, industry and laboratories across a wide range of biological and medical fields.

View the FRAME Strategic Plan 2019 – 2022

Who is FRAME?

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