Projects
FRAME carries out a wide range of projects to help us research and develop new and more effective methods in our mission to find alternatives to animal testing.
Our projects include both lab-based and office-based research. Below are some examples of existing and previous projects that FRAME has been involved with.
Current research projects at the FRAME Alternatives Laboratory
A selection of posters that show the current research projects taking place at the FRAME Alternatives Laboratory.
Pupils views on learning about animal experiments
Undergraduate students from Nottingham Trent University have worked on behalf of FRAME with the aim of promoting engagement with the issues affecting animal experimentation and
Xenotransplantation survey
Between April 2014 and March 2015, 429 patients died waiting for an organ transplant in the UK. A further 807 patients were removed from the transplant list as deteriorating health
Transgenic mouse models for α-synuclein effects in Parkinson’s disease
FRAME carried out a review of mouse models used to study Parkinson’s disease. The findings were presented by intern Michelle Maurer from Johannes Gutenberg University of Mainz,
Using non‐animal methods to avoid human adverse drug reactions
FRAME Scientific Director Dr Gerry Kenna gave a lecture at the Dr Hadwen Trust Animal Replacement Science Conference. His topic was Using non‐animal methods to predict and avoid
Human bone models in vitro
The FRAME Alternatives Lab is able to differentiate human mononuclear blood cells into human osteoclasts (bone eating cells). Osteoclast dysfunction has been observed in a variety of
In vitro models of diabetes
Much of the research into obesity and diabetes is carried out using transgenic animal models. FRAME’s experience and that of many others is that such animal models are of little
New skin model
It is well known that lipids (fatty substances) can have a positive effect on skin. A new project at the FRAME laboratory will enable close investigation of how lipids are absorbed to