In vitro models of diabetes

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In vitro models of diabetes

Much of the research into obesity and diabetes is carried out using transgenic animal models. FRAME’s experience and that of many others is that such animal models are of little use when trying to study human diseases and responses to potential therapies. The FRAME Alternatives Laboratory cultures primary human adipocytes and skeletal muscle myotubes to study the effects of increased fat and carbohydrate levels on the metabolism and gene expression of human fat and muscle tissue.

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